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ea0029oc10.5 | Pituitary Clinical 2 | ICEECE2012

Once-weekly, CTP-modified hGH (MOD-4023) is effective in growth hormone deficient adults: a phase II, dose and frequency finding study

Popovic V. , Goth M. , Vanuga P. , Payer J. , Pfeifer M. , Bidlingmaier M. , Fima E.

Objective: GH replacement therapy currently requires daily injections, which may cause poor compliance and distress for patients. CTP-modified hGH (MOD-4023) is being developed for once-weekly administration in GH Deficient adults and children. The present study evaluated the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of MOD-4023 in GHD adults.Design and methods: 39 normalized GHDA patients currently treated with daily GH were randomized and...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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